Thursday, January 31, 2013

Video: BP ordered to pay $4 billion



>>> a federal judge in new orleans has approved a deal calling for bp to pay a record $4 billion in criminal penalties from the deepwater horizon spill, the worst environmental disaster of all time. it includes manslaughter charges for the 11 workers who died on the rig. the judge called it just punishment for what has happened.

Source: http://video.msnbc.msn.com/nightly-news/50632797/

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Washington Wrestling Report rankings

Published: Wednesday, January 30, 2013, 8:23 p.m.

Below are the latest ranking by WWR, a website run by Dave Gilbertson. Click here for the full rankings.

Class 4A

106
1. Fabian Wickham, Eastmont, Jr.
2. Michael Soler, Lake Stevens, Fr.
7. AJ Crew, Lake Stevens, Fr.
8. Jeremy Nygard, Arlington, Fr.
9. Tyler Headland, Lake Stevens, So.

113
1. Darren Harris, Yelm, So.
4. Alex Rodorigo, Lake Stevens, So.
7. Ruben Crew, Lake Stevens, Fr.
10. Josh Heitzman, Kamiak, Sr.

120
1. Noah Cuzzetto, Edmonds-Woodway, Jr.
5. Jake Douglas, Lake Stevens, Fr.

126
1. Blake Beard, Central Valley, So.
2. Gino Obregon, Cascade, Jr.
6. Luis Reyna, Mount Vernon, Jr.
12. Zach Cunningham, Lake Stevens, Jr.

132
1. Coltan Orrino, Central Valley, Jr.
2. Jesse Petterson, Lake Stevens, Sr.
12. Rafael Ibarra, Mount Vernon, Jr.
14. Matthew Calkins, Lynnwood, Jr.

138
1. Eric Soler, Lake Stevens, Sr.
5. Greg Eagle, Snohomish, Sr.
7. Nathan Vulliet, Edmonds-Woodway, Jr.
9. Bryce Thomas, Arlington, Jr.
12. Connor Gonzales, Arlington, Jr.

145
1. Ian Steen, Graham-Kapowsin, Sr.
6. Scotty Bardel, Arlington, Jr.
11. Andrew Villablobos, Mariner, Jr.
12. Juan Garcia, Cascade, Jr.

152
1. Trevor Anderson, Bethel, Sr.

160
1. Tyler McLean, Mead, Sr.
3. Matt Cuzzetto, Edmonds-Woodway, Sr.
5. Hunter Lord, Lynnwood, Jr.
9. Logan Johnson, Lake Stevens, Jr.
12. Blake Sander, Lake Stevens, Sr.
16. Tanner Perry, Snohomish, Sr.

170
1. Chandler Rogers, Mead, Jr.
6. Cody Vigoren, Lake Stevens, So.
7. Marq Brown, Edmonds-Woodway, Sr.
9. Tyler Kunard, Kamiak, Jr.

182
1. Ryan Christensen, Woodinville, Jr.

195
1. Joe Gomez, Graham-Kapowsin, Sr.
3. Tristan Baus, Snohomish, Jr.

220
1. Matt Voss, Pullayup, Jr.
4. Shaquille Reed, Lake Stevens, Sr.
13. Mario Rojas, Snohomish, Jr.

285
1. Brandon Johnson, Lake Stevens, Sr.
5. George Johanson, Edmonds-Woodway, Sr.

Class 3A

106
1. Kwest Osborn, University, Sr.

113
1. Jesse Barajas, Sunnyside, Jr.
9. West Weinert, Stanwood, So.
11. Nathan McCaughan, Stanwood, So.

120
1. Matthew Iwicki, Eastside Catholic, So.
5. Jacob Cole, Stanwood, Jr.

126
1. Josh Newberg, Kelso, Sr.
2. Matthew Floresca, Shorewood, Jr.
6. John Kim, Glacier Peak, Jr.
9. Ryan Daurie, Marysville Pilchuck, So.
10. Jeremy Vester, Oak Harbor, So.

132
1. Tyler Wicken, Kelso, Jr.
6. Cody Fakkema, Oak Harbor, Sr.
8. Jahleel Vester, Oak Harbor, Jr.

138
1. Terrence McKinney, Shadle Park, Sr.
2. Jessie Lopez, Everett, Sr.
11. Nathaniel Zinkand, Stanwood, Sr.

145
1. Lucas Somera, Enumclaw, Sr.
10. Nate Tibbott, Meadowdale, Sr.
12. Mark Johnston, Oak Harbor, So.

152
1. Izaec Quintanilla, North Central, So.
2. Jacob Elledge, Glacier Peak, Sr.
10. Killian Page, Marysville Pilchuck, So.

160
1. Morgan Smith, Meadowdale, Sr.
2. Joshua Crebbin, Oak Harbor, Sr.
3. Zack Schut, Stanwood, Sr.
9. Tyler Sabin, Glacier Peak, Sr.

170
1. Sisto Pina, Kamiakin, Sr.
4. Drew Hatch, Marysville Pilchuck, So.
6. Syd Springberg, Mountlake Terrace, Jr.
9. Anthony Hawkins, Everett, Jr.

182
1. Sean Elledge, Glacier Peak, Jr.
6. Rick Stewart, Everett, So.
9. Anthony Ortega, Stanwood, So.

195
1. Tanner Orndorff, University, Sr.
5. Ciaran Ball, Meadowdale, Jr.
9. Sam Alexander, Ferndale, Sr.

220
1. Stone Hart, Timberline, Sr.
8. Kam Williams, Ferndale, Sr.
9. Tim Smith, Meadowdale, So.

285
1. Kyle Gleed, Decatur, Sr.
8. Mosese Fifita, Glacier Peak, So.
9. Alfredo Diaz, Marysville Getchell, Sr.
12. Josh Smith, Stanwood, Sr.

Class 2A

106
1. Anthony Barrera, Othello, Sr.
3. Bailey McBride, Cedarcrest, So.
10. Login Corbin, Granite Falls, So.

113
1. Fred Green, Orting, So.
14. Callen Martinez, Cedarcrest, Jr.

120
1. Jake Konzal, Deer Park, Sr.
8. Ryan Nash, Granite Falls, Sr.

126
1. Cole Harris, Deer Park, Sr.
6. Tyler Groff, Granite Falls, Jr.
13. Collin Ferrell, Archbishop Murphy, Sr.
16. James Mackenzie, Sultan, So.

132
1. Gabe Meyer, East Valley (Spok), So.
5. Curtis Chittenden, Cedarcrest, Sr.
12. Drake Mosteller, Lakewood, Jr.
14. Bryce MacDicken, Sultan, Sr.

138
1. Joe Grable, Deer Park, Jr.
11. Ely Malametz, Cedarcrest, So.

145
1. Jake Velarde, North Kitsap, Sr.

152
1. Kellen Pelzel, Centralia, Sr.
7. Nick Decker, Cedarcrest, Sr.
9. Jason Barrus, Sultan, Sr.

160
1. Bobby Reece, Kingston, Jr.
4. Carlos Toledano, Cedarcrest, Sr.

170
1. Anton Yates, East Valley (Yak.), Sr.

182
1. Elias Mason, Cheney, Sr.
7. Jacob Naslund, Sultan, Sr.

195
1. John White, Ridgefield, Sr.
6. Foster Wade, Archbishop Murphy, Jr.

220
1. Jace Malek, West Valley (Spok.), So.
5. Taylor Comfort, Sultan, Jr.
15. James Giorgio, Lakewood, Sr.

285
1. Jaime Miranda, Aberdeen, Sr.
10. Dakota Creed, Archbishop Murphy, Sr.
13. Trystan Nelson, Lakewood, Jr.
16. Hank Sherman, Sultan, Sr.

Source: http://www.heraldnet.com/article/20130130/BLOG18/701319945

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Chrysler profit jumps on higher sales

(AP) ? Just three years out of bankruptcy, Chrysler posted a $1.7 billion profit in 2012 and said it expects to earn more than $2 billion this year.

Improving U.S. auto sales ? and better products at Chrysler ? were the big reasons for the vast improvement over 2011's profit of $183 million. Chrysler sold 2.2 million cars and trucks worldwide last year, up 18 percent.

In the U.S., its largest market, Chrysler's sales rose 21 percent. Chrysler saw strong sales of the Chrysler 200 and 300 sedans, the Jeep Grand Cherokee and the Ram pickup. The Fiat 500 also sold well last year.

The results mark another step in Chrysler's remarkable turnaround. The company filed for bankruptcy during the recession in 2009 and needed a $12.5 billion loan from taxpayers to survive. Chrysler has repaid $11.2 billion, but the U.S. Treasury Department says it won't recover the remaining $1.3 billion. The profit In 2011 was Chrysler's first annual profit since 1997.

Revenue increased 20 percent to $65.8 billion.

The No. 3 U.S. automaker expects net income to rise to around $2.2 billion this year on revenue of between $72 billion and $75 billion. It says worldwide vehicle shipments should reach 2.6 million to 2.7 million, up from 2.4 million last year.

Chrysler's report comes a day after Ford Motor Co. ? No. 2 in the U.S. ? said it expects to see strong results again this year in North America, but warned of widening losses in Europe. General Motors Co. reports 2012 results on Feb. 14.

Chrysler is now majority owned by Italian automaker Fiat SpA. Sergio Marchionne, CEO of both companies, told the company's 63,643 workers in an email that they would get performance bonus payments, although the amounts were not specified.

"The credit for our turnaround is yours," he told the workers, including 43,000 in the U.S. "There can be no more doubt that our comeback is real. Your phenomenal efforts have put us on a road with an endless horizon in front of us."

In slides posted on its website, Chrysler said it plans to roll out several new and updated vehicles this year and beyond:

? A new small crossover SUV this year to replace the aging Jeep Liberty. Updates to the Grand Cherokee large SUV and the Compass small SUV.

? A new Ram commercial van will debut this year, as well as updated heavy-duty Ram pickup.

? An unspecified new Alfa Romeo vehicle for North America this year.

? A new version of the Chrysler 200 midsize sedan, to debut in 2014.

? The previously announced long version of the Fiat 500 mini-car. No more new products until 2015, when the brand gets up to six new models.

Marchionne also said a new minivan is coming in 2015, but it and other new products have been delayed by a lack of money. "We could have moved on the minivan faster if we had unrestricted access to cash," he said. Chrysler says it spent $4 billion on capital expenditures last year, and it plans to hold that about steady in 2013.

He also said he wants Fiat to fully own Chrysler "as soon as I can afford it." Fiat now owns 58.5 percent of Chrysler, with the rest owned by a health care trust for retired union workers. The trust has asked Chrysler to start the process of a public stock offering so it can sell its shares. Chrysler says the process will take eight to nine months.

"I don't see the future of Fiat and Chrysler as being separate, "Marchionne said. "I see them as one entity at some point in time."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-01-30-US-Earns-Chrysler/id-90cc4c8986934ec8927606fa983c1f27

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World Chefs: Thomson dishes up Washington state from Seattle to Spokane

NEW YORK (Reuters) - When food writer Jess Thomson moved to Seattle, Washington, she expected to find the adventuresome cooking for which the city is famous. But she admits to being pleasantly surprised by the rich diversity of the rest of the state.

The 150 recipes in her book "Dishing Up Washington" attempt to capture the authentic regional flavors of the entire state, from Seattle to Spokane, Yakima to Walla Walla.

"It is a total food heaven," said Thomson, cookbook author, recipe developer and food blogger. "I knew it would be delicious but I'm not sure I knew how much would be available here and how constantly I would be bombarded with really great food."

She spoke to Reuters about discovering the distinctive foods of Washington and the state's climate and locavore tradition.

Q: Is this your first cookbook?

A: "This is my fourth cookbook; three in my name, one that I ghostwrote."

Q: Did you write the recipes for this book?

A: "The book is a little bit unique because it is about 60 percent recipes that I've written inspired by the state's ingredients and about 40 percent recipes by chefs, farmers and artisans from all over the state."

Q: What was your purpose with this book?

A: "I wanted to show not just best restaurants but ingredients that drive those restaurants -- what it's like to run a potato farm and the simple potato soup the farmer's mother makes, which is super warming, super delicious but not high-falutin chef-y approach that I think many Seattle chefs might have taken ... I wanted to show the guy who grows saffron on the Olympic peninsula, and the tomato grower in northeastern Washington. She doesn't have a restaurant but she's important to the state because she grows these really fantastic tomatoes."

Q: How would you characterize the cuisine of Washington State?

A: "It's adventuresome coastal cooking that depends heavily on local ingredients."

Q: Which ingredients are typical of the state?

A: "Stone fruits like peaches and cherries are huge here; tree fruits like apples and pears; fish and shellfish, mainly crab, oysters, mussels, and salmon. Then there's really great dairy and cheese, mostly from the northwestern part of the state. The state is also well known for larger crops like grapes, wheat and beef."

Q: How does Seattle's famously rainy climate affect the cuisine?

A: "The state is sort of divided by the Cascade Mountains into two distinct climates: the wet half towards the west and the drier half towards the east ... (But) there's a giant misconception about the rain here. Boston gets more rain than Seattle, but Seattle gets it almost every day of the week in winter. From a food perspective this is a very good climate for growing. Drought is not really an issue here. On the eastern side drought is an issue but many areas there get more than 300 days of sunshine in a year, so the growing season is very long and the conditions are great."

Q: What accounts for the strong locavore tradition?

A: "Because it's available. Farmers' markets near me are open the year round. In February maybe I can't buy cherries but I can buy great kale, radicchio and hazelnuts. I think it's such a vibrant community because the weather allows us to get food year round. The food world doesn't shut down from November to April here."

Q: Who is your book aimed at?

A: "I wanted to make it approachable for people cooking anywhere. The chef recipes are a little more complicated and difficult. The recipes that I've written are much simpler ... This book also an edible tour guide to the state. People tell me they're using it as a travel guide, keeping it in their car as a way of deciding what restaurants to go to in Seattle and the state."

Northwest Crab Chowder

2 tablespoons unsalted butter

1 yellow onion, finely chopped

4 stalks celery, cut into quarter-inch slices

1 tablespoon finely chopped fresh thyme

Salt

Freshly ground black pepper

2 pounds Yukon Gold potatoes (about 7 medium), cut into half-inch chunks

2 cups whole milk

1 cup heavy cream

1 (15-ounce) can fish broth

1 (8-ounce) bottle clam juice

1.5 pounds Dungeness crabmeat, chopped

6 servings

1. Melt the butter in a large soup pot over medium heat. Add the onions, celery, and thyme. Salt and pepper to taste, and cook, stirring, until the vegetables start to soften, about 5 minutes. Add the potatoes, milk, cream, fish broth and clam juice. Bring the soup to a simmer and cook until the potatoes are soft, about 10 minutes.

2. Transfer about 2 cups of the vegetables to a food processor or a blender, blend until smooth, and return to the pot. Stir in the crabmeat, cook for 5 minutes longer, and salt and pepper to taste. Serve piping hot.

(Editing by Patricia Reaney and Doina Chiacu)

(This story corrects spelling of Thomson in slug, headline and throughout)

Source: http://news.yahoo.com/world-chefs-thomson-dishes-washington-state-seattle-spokane-172607626.html

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Retailer planning jobs for spring season

LOUISVILLE, KY (WAVE) - Winter is not quite over, but a home-improvement retailer is already looking forward to spring.

Lowe's plans to hire 45,000 seasonal workers ahead of the busy season.

Seasonal employees will work an average of 20 to 25 hours per week and the length of employment will vary.

Most of the jobs will begin in the spring and could last until September.

For more information or to apply for the positions, click here.

Copyright 2013 WAVE News.?All rights reserved.?

Source: http://stmatthews-lyndon.wave3.com/news/news/112427-retailer-planning-jobs-spring-season

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A-Rod denies PED use report; MLB investigates

FILE - In this Wednesday, Oct. 17, 2012 file photo, New York Yankees' Alex Rodriguez takes batting practice before Game 4 of the American League championship series against the Detroit Tigers, in Detroit. Major League Baseball says it is "extremely disappointed" about a new report that says records from an anti-aging clinic in the Miami area link Rodriguez and other players to the purchase of performance-enhancing drugs. (AP Photo/Carlos Osorio, File)

FILE - In this Wednesday, Oct. 17, 2012 file photo, New York Yankees' Alex Rodriguez takes batting practice before Game 4 of the American League championship series against the Detroit Tigers, in Detroit. Major League Baseball says it is "extremely disappointed" about a new report that says records from an anti-aging clinic in the Miami area link Rodriguez and other players to the purchase of performance-enhancing drugs. (AP Photo/Carlos Osorio, File)

FILE - In this Oct. 18, 2012 file photo, New York Yankees' Alex Rodriguez prepares to hit in the sixth inning during Game 4 of the American League championship series against the Detroit Tigers in Detroit. Major League Baseball says it is "extremely disappointed" about a new report that says records from an anti-aging clinic in the Miami area link Rodriguez and other players to the purchase of performance-enhancing drugs. (AP Photo/Matt Slocum, File)

This undated booking photo provided by the Miami-Dade Police Department, on Tuesday, Jan 29, 2013, shows Anthony Bosch. Major League Baseball says it is "extremely disappointed" about a new report that says records from an anti-aging clinic in the Miami area link New York Yankees star Alex Rodriguez and other players to the purchase of performance-enhancing drugs. The Miami New Times said in a story on Tuesday that it had obtained files through an employee at a recently closed clinic called Biogenesis. The report said that the notes of clinic chief Bosch list the players' names and the substances they received, including human growth hormone and steroids. (AP Photo/Miami-Dade Police Department)

FILE - In this Aug. 12, 2012, file photo, Oakland Athletics starter Bartolo Colon tosses the ball after Chicago White Sox's Gordon Beckham hit a two-run single during the sixth inning of a baseball game in Chicago. Major League Baseball says it is "extremely disappointed" about a new report that says records from an anti-aging clinic in the Miami area link Alex Rodriguez and other players to the purchase of performance-enhancing drugs. The Miami New Times said in a story Tuesday, Jan. 29, 2013, that it had obtained files through an employee at a recently closed clinic called Biogenesis. Other players named by the publication as appearing in the records include Colon, Melky Cabrera, Gio Gonzalez and Nelson Cruz.(AP Photo/Nam Y. Huh, File)

FILE - In this June 12, 2012, file photo, Texas Rangers' Nelson Cruz breaks his bat while hitting a double during the second inning of their baseball game against the Los Angeles Angels in Anaheim, Calif. Major League Baseball says it is "extremely disappointed" about a new report that says records from an anti-aging clinic in the Miami area link Alex Rodriguez and other players to the purchase of performance-enhancing drugs. The Miami New Times said in a story Tuesday, Jan. 29, 2013, that it had obtained files through an employee at a recently closed clinic called Biogenesis. Other players named by the publication as appearing in the records include Cruz, Melky Cabrera, Gio Gonzalez and Bartolo Colon. (AP Photo/Mark J. Terrill, File)

(AP) ? Alex Rodriguez denied a newspaper report that accused him of buying human growth hormone and other performance-enhancing substances from a Miami-area clinic.

The Miami New Times, an alternative weekly, reported Tuesday that it obtained records detailing purchases by Rodriguez, Melky Cabrera, Gio Gonzalez, Bartolo Colon, Nelson Cruz and Yasmani Grandal from a clinic called Biogenesis, run by Anthony Bosch. The paper also posted copies of what it said were Bosch's handwritten records, obtained through a former Biogenesis employee.

Rodriguez admitted four years ago that he used PEDs from 2001-03. Cabrera, Colon and Grandal were suspended for 50 games each last year by MLB following tests for elevated testosterone.

"We are always extremely disappointed to learn of potential links between players and the use of performance-enhancing substances," MLB said in a statement. "Only law enforcement officials have the capacity to reach those outside the game who are involved in the distribution of illegal performance-enhancing drugs. ... We are in the midst of an active investigation and are gathering and reviewing information."

A baseball official, speaking on condition of anonymity because he was not authorized to make public statements, said Monday that MLB did not have any documentation regarding the allegations. If MLB does obtain evidence, the players could be subject to discipline. First offenses result in a 50-game suspension and second infractions in 100-game penalties. A third violation results in a lifetime ban.

Rodriguez is sidelined for at least the first half of the season after hip surgery Jan. 16. A 50-game suspension would cost him $7.65 million of his $28 million salary.

"The news report about a purported relationship between Alex Rodriguez and Anthony Bosch are not true," Rodriguez said in a statement issued by a publicist. "He was not Mr. Bosch's patient, he was never treated by him and he was never advised by him. The purported documents referenced in the story ? at least as they relate to Alex Rodriguez ? are not legitimate."

Jay Reisinger, a lawyer who has presented Rodriguez in recent years, said the three-time AL MVP had retained Roy Black, an attorney from Rodriguez's hometown of Miami. Black's clients have included Rush Limbaugh and William Kennedy Smith.

Rodriguez spent years denying he used PEDs before Sports Illustrated reported in February 2009 that he tested positive for two steroids in MLB's anonymous survey while with the Texas Rangers in 2003. Two days later, he admitted in an ESPN interview that he used PEDs over a three-year period. He has denied using PEDs after 2003.

If the new allegations were true, the Yankees would face high hurdles to get out of the final five years of Rodriguez's contract, which call for him to receive $114 million. Because management and the players' union have a joint drug agreement, an arbitrator could determine that any action taken by the team amounted to multiple punishments for the same offense.

The Yankees said "this matter is now in the hands of the commissioner's office" and said they will not comment further until MLB's investigation ends.

Gonzalez posted on his Twitter feed: "I've never used performance enhancing drugs of any kind and I never will, I've never met or spoken with tony Bosch or used any substance provided by him. anything said to the contrary is a lie."

Colon was not issuing a statement, agent Adam Katz said through spokeswoman Lisa Cohen. Sam and Seth Levinson, the agents for Cabrera and Cruz, did not immediately respond to emails seeking comment.

Cruz and Gonzalez had not previously been linked to performance-enhancing drugs. Cruz's team, the Texas Rangers, said it notified MLB last week after being contacted by the New Times.

The New Times report said it obtained notes by Bosch listing the players' names and the substances they received. Several unidentified employees and clients confirmed to the publication that the clinic distributed the substances, the paper said. The employees said that Bosch bragged of supplying drugs to professional athletes but they never saw the sports stars in the office.

Rodriguez appears 16 times in the documents it received, the paper said, either as "Alex Rodriguez," ''Alex Rod" or the nickname "Cacique," a pre-Columbian Caribbean chief. The paper said the records list that Rodriguez paid for HGH; testosterone cream; IGF-1, a substance banned by baseball that stimulates insulin production; and GHRP, which releases growth hormones.

Rodriguez's cousin, Yuri Sucart, also is listed as having purchased HGH. Sucart was banned from the Yankees clubhouse, charter flights, bus and other team-related activities by MLB in 2009 after Rodriguez said Sucart obtained and injected PEDs for him.

Also listed among the records, according to the New Times, are tennis player Wayne Odesnik, Cuban boxer Yuriorkis Gamboa and Jimmy Goins, the strength and conditioning coach of the University of Miami baseball team.

Mia Ro, a spokeswoman for the federal Drug Enforcement Administration in Miami, said she could not confirm or deny the existence of an investigation in Bosch or the clinic.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-01-29-MLB-Drug%20Investigation/id-850bdca282564cb69512f7ff55c8ff71

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Wednesday, January 30, 2013

Scientists learn more about how inhibitory brain cells get excited

Jan. 30, 2013 ? Scientists have found an early step in how the brain's inhibitory cells get excited. A natural balance of excitement and inhibition keeps the brain from firing electrical impulses randomly and excessively, resulting in problems such as schizophrenia and seizures. However excitement is required to put on the brakes.

"When the inhibitory neuron is excited, its job is to suppress whatever activity it touches," said Dr. Lin Mei, Director of the Institute of Molecular Medicine and Genetics at the Medical College of Georgia at Georgia Regents University and corresponding author of the study in Nature Neuroscience.

Mei and his colleagues found that the protein erbin, crucial to brain development, is critical to the excitement.

It was known that a protein on the cell surface called TARP gamma-2, also known as stargazing, interacts with a brain cell receptor called AMPA, ensuring the receptor finds the cells surface. It is here that the receptor can be activated by the neurotransmitter glutamate. AMPA receptor activation is essential to activation of the NMDA receptor, which enables cells to communicate, ultimately enabling learning and memory, Mei said. How TARP gamma-2 was controlled, was an unknown.

Inside the nucleus of inhibitory cells in areas of the brain that control learning and memory, the researchers found erbin interacts with TARP gamma-2, enabling it to survive. "If you do not have this mechanism, your stargazing becomes very unstable and your AMPA receptor cannot be on the surface so this neuron is inactive," Mei said. They also found that erbin is only in these inhibitory neurons, called interneurons. They're already working on what they believe to be the counterpart for excitatory cells, which account for about 80 percent of brain cells.

"Interneurons basically control firing," releasing GABA, a major inhibitory neurotransmitter, Mei said. They tone down or synchronize the activity of pyramidal cells, pyramid-shaped neurons that get both excitatory and inhibitory input then make the call on what action to take.

When scientists ablated the erbin gene in mice or kept erbin from interacting with TARP gamma-2, a protein that helps anchor the AMPA receptor on the cell surface, TARP gamma-2 couldn't do its job. The result was less receptors on the cell surface and mice that were hyperactive with impaired learning and memory.

Cell activity hinges on receptor activity and receptors must be anchored on the cell surface to work. Ensuring AMPA receptors are strategically placed is a lifelong task since the busy receptors wear out and each brain cell has tons of them, Mei said.

He and his colleagues reported in the journal, Neuron, in 2007, two genes -- neuregulin-1 and its receptor ErbB4 -- that help maintain a healthy balance of excitement and inhibition by releasing GABA at the sight of inhibitory synapses, the communication paths between neurons. Years before, they showed the genes were also at excitatory synapses, where they also could quash activation. Both genes are involved in human development and implicated in schizophrenia and cancer.

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Story Source:

The above story is reprinted from materials provided by Georgia Health Sciences University. The original article was written by Toni Baker.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Yanmei Tao, Yong-Jun Chen, Chengyong Shen, Zhengyi Luo, C Ryan Bates, Daehoon Lee, Sylvie Marchetto, Tian-Ming Gao, Jean-Paul Borg, Wen-Cheng Xiong, Lin Mei. Erbin interacts with TARP ?-2 for surface expression of AMPA receptors in cortical interneurons. Nature Neuroscience, 2013; DOI: 10.1038/nn.3320

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/5e3pfQjjfxE/130130121641.htm

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Artificial pancreas: The way of the future for treating type 1 diabetes

Jan. 28, 2013 ? IRCM researchers, led by endocrinologist Dr. R?mi Rabasa-Lhoret, were the first to conduct a trial comparing a dual-hormone artificial pancreas with conventional diabetes treatment using an insulin pump and showed improved glucose levels and lower risks of hypoglycemia. Their results, published January 28 in the Canadian Medical Association Journal (CMAJ), can have a great impact on the treatment of type 1 diabetes by accelerating the development of the external artificial pancreas.

The artificial pancreas is an automated system that simulates the normal pancreas by continuously adapting insulin delivery based on changes in glucose levels. The dual-hormone artificial pancreas tested at the IRCM controls glucose levels by automatically delivering insulin and glucagon, if necessary, based on continuous glucose monitor (CGM) readings and guided by an advanced algorithm.

"We found that the artificial pancreas improved glucose control by 15 per cent and significantly reduced the risk of hypoglycemia as compared with conventional insulin pump therapy," explains engineer Ahmad Haidar, first author of the study and doctoral student in Dr. Rabasa-Lhoret's research unit at the IRCM and at the Department of Electrical and Computer Engineering at McGill University. "The artificial pancreas also resulted in an 8-fold reduction of the overall risk of hypoglycemia, and a 20-fold reduction of the risk of nocturnal hypoglycemia."

People living with type 1 diabetes must carefully manage their blood glucose levels to ensure they remain within a target range. Blood glucose control is the key to preventing serious long-term complications related to high glucose levels (such as blindness or kidney failure) and reduces the risk of hypoglycemia (dangerously low blood glucose that can lead to confusion, disorientation and, if severe, loss of consciousness).

"Approximately two-thirds of patients don't achieve their target range with current treatments," says Dr. Rabasa-Lhoret, Director of the Obesity, Metabolism and Diabetes research clinic at the IRCM. "The artificial pancreas could help them reach these targets and reduce the risk of hypoglycemia, which is feared by most patients and remains the most common adverse effect of insulin therapy. In fact, nocturnal hypoglycemia is the main barrier to reaching glycemic targets."

"Infusion pumps and glucose sensors are already commercially-available, but patients must frequently check the sensor and adjust the pump's output," says Mr. Haidar. "To liberate them from this sizable challenge, we needed to find a way for the sensor to talk to the pump directly. So we developed an intelligent dosing algorithm, which is the brain of the system. It can constantly recalculate insulin dosing based on changing glucose levels, in a similar way to the GPS system in a car, which recalculates directions according to traffic or an itinerary change."

The researchers' algorithm, which could eventually be integrated as software into a smart phone, receives data from the CGM, calculates the required insulin (and glucagon, if needed) and wirelessly controls the pump to automatically administer the proper doses without intervention by the patient.

"The system we tested more closely mimics a normal pancreas by secreting both insulin and glucagon," adds Dr. Laurent Legault, peadiatric endocrinologist and outgoing Director of the Insulin Pump Centre at the Montreal Children's Hospital, and co-author of the study. "While insulin lowers blood glucose levels, glucagon has the opposite effect and raises glucose levels. Glucagon can protect against hypoglycemia if a patient with diabetes miscalculates the necessary insulin dose."

"Our work is exciting because the artificial pancreas has the potential to substantially improve the management of diabetes and reduce daily frustrations for patients," concludes Dr. Rabasa-Lhoret. "We are pursuing our clinical trials to test the system for longer periods and with different age groups. It will then probably be introduced gradually to clinical practice, using insulin alone, with early generations focusing on overnight glucose controls."

This study was conducted with 15 adult patients with type 1 diabetes, who had been using an insulin pump for at least three months. Patients were admitted twice to the IRCM's clinical research facility and received, in random order, both treatments: the dual-hormone artificial pancreas and the conventional insulin pump therapy. During each 15-hour visit, their blood glucose levels were monitored as they exercised on a stationary bike, received an evening meal and a bedtime snack, and slept at the facility overnight.

Dr. Rabasa-Lhoret's research is funded by Diabetes Qu?bec, the Canadian Diabetes Association, and the IRCM's J.A. De S?ve Chair in clinical research. IRCM collaborators who contributed to study include Maryse Dallaire, Ammar Alkhateeb, Ad?le Coriati, Virginie Messier and Maude Millette.

About diabetes

Type-1 diabetes is a chronic, incurable disease that occurs when the body doesn't produce enough or any insulin, leading to an excess of sugar in the blood. It occurs most often in children, adolescents or young adults. People with type-1 diabetes depend on insulin to live, either through daily injections or with a pump. Diabetes is a major cause of vision loss, kidney and cardiovascular diseases.

According to the Canadian Diabetes Association, an estimated 285 million people worldwide are affected by diabetes, approximately 10 per cent of which have type 1 diabetes. With a further 7 million people developing diabetes each year, this number is expected to hit 438 million by 2030, making it a global epidemic.?

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Story Source:

The above story is reprinted from materials provided by Institut de recherches cliniques de Montreal.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Ahmad Haidar, Laurent Legault, Maryse Dallaire, Ammar Alkhateeb, Ad?le Coriati, Virginie Messier, Peiyao Cheng, Maude Millette, Benoit Boulet, Chiu-Ching Huang, R?mi Rabasa-Lhoret. Glucose-responsive insulin and glucagon delivery (dual-hormone artificial pancreas) in adults with type 1 diabetes: a randomized crossover controlled trial. Canadian Medical Association Journal, 2013 DOI: 10.1503/cmaj.121265

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/IsBFXJa7YCU/130128151928.htm

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CIS Top 10 Tuesday: UBC Okanagan women's volleyball now 9th ...

CIS Top 10 Tuesday

OTTAWA (CIS)?? There are three changes atop CIS national rankings this week. The UNB Varsity Reds return to #1 in men?s hockey, while the Toronto Varsity Blues and Guelph Gryphons take the lead in women?s and men?s track and field, respectively.

In other CIS sports, Windsor (women?s basketball), Carleton (men?s basketball), McGill (women?s hockey), UBC (women?s swimming & women?s volleyball), Toronto (men?s swimming) and Alberta (men?s volleyball, women?s & men?s wrestling) all maintain their #1 status.

WOMEN?S BASKETBALL
(regular season record) / votes (first-place votes) / (previous rankings)
1. Windsor (15-0) / 515 points (42) / (1)
2. Saint Mary?s (13-0) / 465 (1) / (2)
3. Regina (14-2) / 434 / (3)
4. Fraser Valley (13-3) / 380 / (4)

5. Carleton (13-3) / 352 / (5)
6. UBC (12-4) / 295 / (6)
7. Brock (14-1) / 221 / (7)
8. Calgary (14-2) / 206 / (10)
9. Victoria (11-5) / 172 / (8)

10. Concordia (7-3) / 111 / (9)

Other votes: Acadia (96), Ottawa (71)

MEN?S BASKETBALL
(regular season record) / votes (first-place votes) / (previous rankings)
1. Carleton (15-1) / 491 points (40) / (1)
2. UBC (14-2) / 450 (1) / (2)
3. Cape Breton (14-0) / 410 / (3)
4. Windsor (12-3) / 367 / (5)
5. Acadia (9-3) / 301 / (6)
6. Alberta (13-3) / 299 / (4)
7. Ryerson (12-2) / 265 / (7)
8. Ottawa (12-4) / 130 / (8)
9. Fraser Valley (9-7) / 111 / (NR)
10. McGill (6-3) / 97 / (9)

Other votes:?Saskatchewan (91),?Lakehead (89)

WOMEN?S HOCKEY
(regular season record) / (previous rankings)
1. McGill (15-0-0) / (1)
2. Calgary (20-3-1) / (2)
3. Montreal (13-3-0) / (4)
4. Laurier (19-1-3) / (3)
5. St. FX (19-1-0) / (5)
6. Guelph (18-3-2) / (8)
7. Queen?s (17-3-2) / (6)
8. Alberta (15-8-1) / (7)
9. Western (16-5-1) / (9)
10. Regina (15-7-2) / (10)

MEN?S HOCKEY
(regular season record) / votes (first-place votes) / (previous rankings)
1. UNB (20-5-0) / 151 points (8) / (2)
2. Alberta (19-4-1) / 147 (6) / (1)
3. Western (20-4-0) / 131 (2) / (3)
4. UQTR (18-5-1) / 93 / (7)
5. Saint Mary?s (16-7-2) / 81 / (4)
6. Acadia (16-7-2) / 72 / (6)
7. Saskatchewan (16-7-1) / 69 / (5)
8. Manitoba (15-5-4) / 57 / (9)

9. Carleton (17-6-2) / 30 / (8)
10. Calgary (15-9-0) / 26 / (10)

Other votes: UPEI (12), Guelph (8), Windsor (3)

WOMEN?S SWIMMING
(points) / (previous rankings)
1. UBC 668 points / (1)
2. Calgary 487 / (3)

3. Toronto 281 / (2)
4. Montreal 254 / (4)
5. UQTR 166 / (7)
6. Dalhousie 162 / (5)
7. Alberta 161 / (6)
8. Western 155 / (NR)
9. McMaster 106 / (8)
10. Laval 101 / (NR)

MEN?S SWIMMING
1. Toronto 463 points / (1)
2. Calgary 422 / (5)
3. UBC 396 / (3)
4. Alberta 258 / (2)

5. Laval 214 / (4)
6. Victoria 210 / (7)
7. Western 184 / (NR)
8. Dalhousie 126 / (6)
9. McMaster 113 / (9)
10. Lethbridge 112 / (10)

WOMEN?S TRACK & FIELD
(points) / (previous rankings)
1. Toronto 92 points / (4)
2. Guelph 88 / (2)
3. Calgary 83 / (1)
4. Windsor 76 / (3)
5. Western 47 / (5)
6. Saskatchewan 42 / (6)
7. Trinity Western 41 / (8)

8. Ottawa 31 / (NR)
9. Montreal 26.5 / (NR)
10. Regina 25 / (7)

MEN?S TRACK & FIELD
1. Guelph 101.5 points / (2)
T2. Laval 67 / (7)
T2. Ottawa 67 / (6)
4. Sherbrooke 62.33 / (3)
5. York 59.33 / (4)
6. Western 54.33 / (5)
7. Windsor 52 / (1)
8. Regina 32 / (10)
9. Dalhousie 29.5 / (NR)
10. Calgary 25.83 / (NR)

WOMEN?S VOLLEYBALL
(regular season record) / votes / (previous rankings)
1. UBC (17-1) / 60 points / (1)
2. Trinity Western (16-2) / 56 / (2)

3. Dalhousie (13-2) / 50.5 / (4)
4. Ottawa (15-1) / 46.5 / (7)
5. York (13-1) / 44 / (5)
6. Alberta (13-5) / 43 / (3)
7. Montreal (12-6) / 34.5 / (T10)
8. Laval (14-4) / 33.5 / (6)
9. UBC Okanagan (11-7) / 27 / (8)
10. Sherbrooke (14-4) / 24 / (9)

Other votes:?Mount Royal (21), Calgary (16), Queen?s (8.5), Manitoba (7), Saint Mary?s (5.5).

MEN?S VOLLEYBALL
(regular season record) / votes (first-place votes) / (previous rankings)
1. Alberta (18-0) / 270 points (27) / (1)
2. McMaster (15-0) / 237 (1) / (2)
3. Laval (16-0) / 202 / (3)
4. Manitoba (12-6) / 196 / (4)
5. Trinity Western (13-5) / 182 / (5)
6. Saskatchewan (12-6) / 132 / (8)
7. UBC (12-6) / 117 / (7)
8. Brandon (10-8) / 88 / (6)
9. Winnipeg (8-10) / 48 / (9)

10. Waterloo (13-2) / 40 / (10)

WOMEN?S WRESTLING
(previous rankings)

1. Alberta (1)
2. Brock (2)
3. Regina (3)
4. Western (4)
5. Calgary (5)
6. Saskatchewan (6)

7. Lakehead (7)
8. Concordia (8)
9. McMaster (9)
10. UNB (10)

MEN?S WRESTLING
1. Alberta (1)

2. Concordia (2)
3. Western (3)
4. Brock (4)
5. McMaster (5)
6. Guelph (6)
T7. Regina (T7)
T7. UNB (T7)
9. Saskatchewan (9)
10. Calgary (10)

About Canadian Interuniversity Sport
Canadian Interuniversity Sport is the national governing body of university sport in Canada. Every year, 11,000 student-athletes and 700 coaches from 54 universities and four regional associations vie for 21 national championships in 12 different sports. CIS also provides high performance international opportunities for Canadian student-athletes at Winter and Summer Universiades, as well as numerous world university championships. For further information, visit www.cis-sic.ca or follow us on:

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YouTube

Source: https://news.ok.ubc.ca/athrec/2013/01/29/cis-top-10-tuesday-ubc-okanagan-womens-volleyball-now-9th/

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Would You Buy a Google Chromebook? | DailyTekk

samsung-chromebook-frontviewSince their launch in 2011,?Chromebooks?have slowly been gaining steam. Lenovo just thew their hat into the Chrome OS arena along with Acer and Samsung with a?Chromebook designed for education. Starting at $199, Chromebooks do one thing: launch Chrome and connect to the web. In a world of tablets and smartphones, do Chromebooks matter?at all?in your opinion? Would you buy one/recommend buying one? What do you like or dislike about the idea of a Chromebook? Will businesses get on board? Consumers? What do you think Google is trying to accomplish with the Chromebook? Are Chromebooks (and Chrome OS) an important challenger to Microsoft and Apple? Here?s the Think Tank to give you their opinion:

No, But It?s Perfect for the Google Universe

martyAs of now, I would not buy a Google Chromebook. This is not to say everyone should not buy a one. For most people, the Chromebook is a perfect device since 95 percent of the time the only app most people use is a browser to access the Internet and; for those who primarily live in the Google universe, this is the perfect portable device.

As for me, I?m firmly entrenched in the Apple ecosystem so a Chromebook really would not be a good choice for me. I also work with and edit photography and video so my computers needs are more than just a browser. Along with a 27 inch iMac, the MacBook Air is my notebook computer of choice.

I believe the Chromebook is a transitional device. As tablets and other tablet like device (like smartphones) gain more power and usability, these are the devices that will continue to gain traction. It?s ultimately about portability, versatility and connectivity. A tablet is portable in that you can tuck it under your arm (or in your pocket in the case of the iPad Mini and other 7 inch models,) versatile in that you can use peripherals such as keyboards to add specialized functionality when needed and connected in that most tablet devices have 3G and LTE data connectivity built-in and all have wifi so you can be online from anywhere.

So to answer the question: Would I buy a Google Chromebook? My answer is no but I suspect for most average people who have data needs that are mostly satisfied through a web browser, the answer is a resounding YES!

Marty (@martymcpadden) is the founder and CEO of PodJamTV Productions who also?blogs for the Huffington Post.

Yes and No; It Depends

chrisI ordered a couple of Acer Chromebooks to test out (I wanted to give the Samsung model a try, but they were consistently sold out all across the web) and I have to say I really like them, surprisingly. I can?t replace my normal computing routine with a Chromebook at the moment? I?m too dependent on Adobe Creative Suite which demands a lot more power and obviously needs to be installed locally. But, for many people I know and work with, the Chromebook is perfect?it not only does everything they need, it?s cheap. I wouldn?t be surprised if the Chromebooks became free someday as Google does it?s best to keep people using it?s search, especially in the face on new Facebook Graph Search competition. I wish I could get away with just a web browser? but I still can?t quite do it. If I could, I?d happily use a Chromebook (although I still prefer my MacBook Air, given a choice). It turns on quick, has some nice built-in features like the ability to snap windows (ie Chrome) to either side of the screen. I have an iPad, and I love it, but I am a device guy?a Chromebook is nice to have around just cause? I can pick up and use it anywhere without really worrying if it gets messed up/dropped/scratched/stolen. It?s almost disposable. Secretary?s (and who are we kidding, some executives) can get by on a Chromebook no problem (it has an HDMI out as well for connecting to a monitor or TV). So, yes, and no.

No, But I?d Recommend a Chromebook to My Grandma

chadIt?s not in my budget because if I bought a Chromebook, I?d have to buy another laptop to get actual work done. I don?t need two laptops.

When I think of netbooks, I associate them with crappier versions of every other computer on the market. Who wants one laptop for getting stuff done, and one craptop for checking email and tweeting? No thanks. I?ll use my iPad for that.

So, no. I would not buy a Chromebook. I thought netbooks were dead anyway now that we have iPads. That said, I would recommend a Chromebook to my Grandma if she asked me what kind of computer she should get that isn?t an Apple.

I?m not entirely sure what Google?s M.O. is with Chromebook, but tablets like the iPad have clearly struck a cord with a demographic that historically hasn?t considered using social media or even getting online. The Chromebook may be able to do something that netbooks couldn?t ? get people to buy them. If they do, it will be the OS that earns Google a win for netbooks.

Chad Halvorson (@chadworks)?is the CEO of?thisCLICKS, makers of?When I Work, a cloud-based mobile employee scheduling software.

No, Because I Have an iPad

kerryPersonally, I wouldn?t buy one, but that?s only because I have an iPad already. As a parent and educator, I think there?s absolutely a market for an affordable tool like this. With its low price point, it could even help to bridge the ?Digital Divide? by enabling more people to access the Internet. The Chromebook doesn?t directly compete with Microsoft or Apple, because those companies are reaching for a higher-end market. This could be a useful tool for consumers who otherwise would be priced out of the tablet or laptop market.

Essentially, Chromebooks are good for one thing: accessing the Internet using Chrome. This is fantastic, provided users can do all the things they?d generally want to do online. Video playback on some major sites ? including Netflix ? doesn?t work properly on the Chromebook, which limits the appeal of this tool for recreational and educational purposes. If they can sort that out, this could be a viable option for a largely untapped market.

Kerry O?Shea Gorgone (@KerryGorgone) is an attorney, new media specialist, and educator teaching Internet marketing at Full Sail University in Florida.

No, But I?d Buy One for My Son

kimNo, I wouldn?t buy a Google Chromebook, well, at least not for myself. I?m seriously considering buying one for a certain someone in my family who just happens to have a birthday right around the corner, though (hint, hint).

I have a Macbook Pro that I?m very happy with. However, I do wish the Google Chromebook had been an option back when I purchased my Mac laptop, which certainly didn?t come cheap. Ranging between $199 and $249, a Chromebook would have been a much more budget-appropriate choice.

I would consider purchasing a Samsung Chromebook for my almost 12-year-old. (Shh! Don?t tell him.) It would be a perfect low-cost first laptop for him. As a 6th grader who wrestles a grip of homework, reports, and presentations, he has to quickly create, edit, cloud share, and email text documents, spreadsheets, and image and video files on the fly. He could easily do all of that (via Google Drive, Gmail and such) and much more (IM and explore the web, hopefully not too much) with a Chromebook, all while seamlessly syncing it with with his Android smartphone.

Despite rumors that Chromebooks only do one thing (access the Internet and not much more), they?re actually packed with quite a few top notch built-in apps and utilities, including a native media player, photo editor, and many more built-in geeky goodies. Plus, I hear they?re pretty much bulletproof when it comes to viruses and malware.

Bonus: With a Chromebook, my tween (and don?t tell him I called him that, he?d be mortified) could easialy listen to music and stream movies via YouTube and Google Play. Both are nearly impossible to sanitize in terms of age-appropriate content, though. Chromebook at his fingertips, my son could even chat with up to nine friends all at once via Google Hangouts, though I?m not sure I?m quite ready for him to take the way-too-public required Google+ social media plunge.

And how could he survive without a million games to conquer? It?s a good thing the Chrome Web Store features countless fun (and free!) games, including a few of my son?s favorites, like Motocross Nitro, Mini Ninjas, Need for Speed World, and, yes, the almighty Minecraft.

Final verdict: I?d definitely buy a budget-friendly Google Chromebook over a pricey Macbook for my kids (the other two will want what their big brother has, no doubt). If someone spills Gatorade on it or drops it in the pool, I won?t be out a thousand bucks. As you can see, a killer price is far from the only reason I?d pick one (or three) up for my brood. Now to figure out where I can get one within walking distance of my home?

Kim Lachance Shandrow?(LinkedIn) is a?Los Angeles-based tech journalist who specializes in writing about social media marketing, startups, smartphones, streaming TV, mobile apps and green technology.

Source: http://dailytekk.com/2013/01/28/would-you-buy-a-google-chromebook/

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Tuesday, January 29, 2013

Bad computer day - Hardware: Computers, Cell Phones & Other ...

:mad: Let me start off with that! What a day for computing. Yesterday, I had a hard drive crash on my desktop, then went to get my 6 month old laptop and when I opened it up, the screen went all pinkish and had horizontal lines flashing through it! Both in one day! Sheesh!

The desktop gave me a warning about a week ago when it all the sudden wouldn't boot up one morning. I ran a repair disc and nothing then all the sudden it did fire up. But yesterday no such luck. The good news is that it uses an SAS RAID storage system which mean that it has a stack of 3 identicle SCSI drives. They all are mirror images of each other. This means no info is lost if one fails. You just get another, and pop it in and off you go. It takes all three to run though so I had to order a new one to replace the blinking(failed) one. It works like a server.

The laptop I wasn't so fortunate although I'm typing this on it right now after fiddling with the calibration so that I could at least see a little better. (crazy pixelation) Tried to uninstall the video drivers and reinstall new ones but no joy. Got HP service (some guy in India) to help but we couldn't fix it. Graphics card is the culprit. They are sending me a free Fedex box and will repair (read: replace ) it for free. While cool, it's a pain as I have to back up everything because they will just send me a new one I'm sure due to the fact that the graphics are onboard the motherboard. Oh well, at least it was still in warrentee.

So that's how my day went! :mad::taz:

Source: http://nepacrossroads.com/about27857.html

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Soldier who lost 4 limbs has double-arm transplant

FILE - In this July 4, 2012 file photo, Army Sgt. Brendan Marrocco of Staten Island, N.Y., wearing a prosthetic arm, poses for a picture at the 9/11 Memorial in New York. Marrocco, 26, the first soldier to survive losing all four limbs in the Iraq war, has received a double-arm transplant in Baltimore. His father, Alex Marrocco, said Monday, Jan. 28, 2013 that his son had the operation on Dec. 18, 2012 at Johns Hopkins Hospital. (AP Photo/Seth Wenig, File)

FILE - In this July 4, 2012 file photo, Army Sgt. Brendan Marrocco of Staten Island, N.Y., wearing a prosthetic arm, poses for a picture at the 9/11 Memorial in New York. Marrocco, 26, the first soldier to survive losing all four limbs in the Iraq war, has received a double-arm transplant in Baltimore. His father, Alex Marrocco, said Monday, Jan. 28, 2013 that his son had the operation on Dec. 18, 2012 at Johns Hopkins Hospital. (AP Photo/Seth Wenig, File)

FILE - In this July 4, 2012 file photo, Army Sgt. Brendan Marrocco of Staten Island, N.Y., left, Marine Cpl. Todd Love of Atlanta, Ga., center, and Marine Cpl. Juan Dominguez of Deming, N.M., pose for a picture at the 9/11 Memorial in New York. Marrocco, 26, the first soldier to survive losing all four limbs in the Iraq war, has received a double-arm transplant in Baltimore. His father, Alex Marrocco, said Monday, Jan. 28, 2013 that his son had the operation on Dec. 18, 2012 at Johns Hopkins Hospital. (AP Photo/Seth Wenig, File)

On Facebook, he describes himself as a "wounded warrior...very wounded."

Brendan Marrocco was the first soldier to survive losing all four limbs in the Iraq War, and doctors revealed Monday that he's received a double-arm transplant.

Those new arms "already move a little," he tweeted a month after the operation.

Marrocco, a 26-year-old New Yorker, was injured by a roadside bomb in 2009. He had the transplant Dec. 18 at Johns Hopkins Hospital in Baltimore, his father said Monday.

Alex Marrocco said his son does not want to talk with reporters until a news conference Tuesday at the hospital, but the younger Marrocco has repeatedly mentioned the transplant on Twitter and posted photos.

"Ohh yeah today has been one month since my surgery and they already move a little," Brendan Marrocco tweeted Jan. 18.

Responding to a tweet from NASCAR driver Brad Keselowski, he wrote: "dude I can't tell you how exciting this is for me. I feel like I finally get to start over."

The infantryman also received bone marrow from the same dead donor who supplied his new arms. That novel approach is aimed at helping his body accept the new limbs with minimal medication to prevent rejection.

The military sponsors operations like these to help wounded troops. About 300 have lost arms or hands in Iraq or Afghanistan.

Unlike a life-saving heart or liver transplant, limb transplants are aimed at improving quality of life, not extending it. Quality of life is a key concern for people missing arms and hands ? prosthetics for those limbs are not as advanced as those for feet and legs.

"He was the first quad amputee to survive," and there have been four others since then, Alex Marrocco said.

The Marroccos want to thank the donor's family for "making a selfless decision ... making a difference in Brendan's life," the father said.

Brendan Marrocco has been in public many times. During a July 4 visit last year to the Sept. 11 Memorial with other disabled soldiers, he said he had no regrets about his military service.

"I wouldn't change it in any way. ... I feel great. I'm still the same person," he said.

The 13-hour operation was led by Dr. W.P. Andrew Lee, plastic surgery chief at Johns Hopkins. It was the seventh double-hand or double-arm transplant done in the United States.

Lee led three of those earlier operations when he worked at the University of Pittsburgh, including the only above-elbow transplant that had been done at the time, in 2010.

Marrocco's "was the most complicated one" so far, Lee said in an interview Monday. It will take more than a year to know how fully Marrocco will be able to use the new arms.

"The maximum speed is an inch a month for nerve regeneration," he explained. "We're easily looking at a couple years" until the full extent of recovery is known.

While at Pittsburgh, Lee pioneered the immune-suppression approach used for Marrocco. The surgeon led hand-transplant operations on five patients, giving them marrow from their donors in addition to the new limbs. All five recipients have done well, and four have been able to take just one anti-rejection drug instead of combination treatments most transplant patients receive.

Minimizing anti-rejection drugs is important because they have side effects and raise the risk of cancer over the long term. Those risks have limited the willingness of surgeons and patients to do more hand, arm and even face transplants.

Lee has received funding for his work from AFIRM, the Armed Forces Institute of Regenerative Medicine, a cooperative research network of top hospitals and universities around the country that the government formed about five years ago. With government money, he and several other plastic surgeons around the country are preparing to do more face transplants, possibly using the new immune-suppression approach.

Marrocco expects to spend three to four months at Hopkins, then return to a military hospital to continue physical therapy, his father said. Before the operation, he had been fitted with prosthetic legs and had learned to walk on his own.

He had been living with his older brother in a specially equipped home on New York's Staten Island that had been built with the help of several charities. Shortly after moving in, he said it was "a relief to not have to rely on other people so much."

The home was heavily damaged by Superstorm Sandy last fall.

Despite being in a lot of pain for some time after the operation, Marrocco showed a sense of humor, his father said. He had a hoarse voice from the tube that was in his throat during the long surgery and decided he sounded like Al Pacino. He soon started doing movie lines.

"He was making the nurses laugh," Alex Marrocco said.

___

Associated Press Writer Stephanie Nano in New York contributed to this report.

___

Online:

Army regenerative medicine:

http://www.afirm.mil/index.cfm?pageid=home

and http://www.afirm.mil/assets/documents/annual_report_2011.pdf

___

Follow Marilynn Marchione at http://twitter.com/MMarchioneAP .

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/bbd825583c8542898e6fa7d440b9febc/Article_2013-01-28-US-Soldier-Transplanted-Arms/id-3fd9ce8dde6942b8b05a148bffde9896

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White BlackBerry Z10 Caught On Film Days Before Its Official Unveiling

whitez10-1After months of stoking anticipation and dealing with criticism, RIM will finally reveal BlackBerry 10 to the world on Wednesday. It's got to be a heady moment for everyone involved -- this is the company's big shot at redemption and relevance -- but until then the rest of us will just have to make do with another batch of leaked BB10 hardware photos.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/mVTlaK9rUOI/

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H.265 video gets approved, sets the stage for more efficient 1080p, eventual 4K

H.256 video gets approved, sets the stage for more efficient 1080p, eventual 4K

H.265, the next generation video codec from the consortium that brought you the current Apple standard, H.264, has been approved by the International telecommunications Union (ITU). In a press release, the ITU said:

The new codec will considerably ease the burden on global networks where, by some estimates, video accounts for more than half of bandwidth use. The new standard, known informally as ?High Efficiency Video Coding? (HEVC) will need only half the bit rate of its predecessor, ITU-T H.264 / MPEG-4 Part 10 ?Advanced Video Coding? (AVC), which currently accounts for over 80 per cent of all web video. HEVC will unleash a new phase of innovation in video production spanning the whole ICT spectrum, from mobile devices through to Ultra-High Definition TV.

Downloading 1080p files that are half the size will be great. When Ultra HD (aka 4K, aka 2160p) goes into broader released, we'll see what file sizes those monsters end up having. at 4 times the pixels, even half the size will still be twice as big as 1080p. And that's if/when Apple chooses to adopt it and integrate support for it into iTunes, and into iOS devices, most especially the Apple TV. Since they only added 1080p last year, it could be a bit of a wait... Hopefully H.265 support for 1080p will be faster.

Either way, nice to see the technology moving forward. My flash storage thanks you!

Source: ITU, thanks Anthony!



Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/N3hxdmOvh8s/story01.htm

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Monday, January 28, 2013

COMPUTER CHESS ? Hammer to Nail

(Computer Chess world premiered in the NEXT Section of the 2013 Sundance Film Festival, where it won the Alfred P. Sloan Feature Film Prize. Its next stop is the Berlin International Film Festival. Visit the film?s totally awesome official website to learn more.)

In 1984 Barry Salt, a rather obscure British film theorist, published a book called Film Style And Technology. In the book, Salt did statistical analysis of key films from each major period of film style history. His basic thesis is that film technology shapes style and aesthetics. The most obvious example is how film grammar changed once sound was introduced. The camera became less mobile due to the early microphones and mixers being bulky, which also prevented location shoots. Stories also became dialogue driven and acting became more voice dependent. So each period has a distinctive feel stylistically due to the particular technological advances of that time. Thus, if you want to make a true period film, one that really feels it is of the past, you would have to draw inspiration from more than just the props, haircuts and wardrobe of that period. Recently, watching a film print of Three Days of the Condor, I realized it felt so uniquely ?seventies? because the lenses, film stock, ratio of wide shots to tight, and general editing pace were all unusual compared to modern films. It succeeded as a total immersion into the distant past in a way that modern period films rarely do.

Andrew Bujaski?s Computer Chess was my favorite of the 28 films I saw at the 2013 Sundance Film Festival. It is a complete and utter cinematic experience, in large part due to it being shot on the Sony AVC 3260, a ?70s-era tethered video tube camera. The camera first hit the market in the late ?60s and was designed as a lightweight portable camera for both professionals and amateurs. Its shallow focus, low contrast black-and-white image looks at first like modern security camera footage, but the Sony has a zoom lens that allows for a wide variety of framings, which provides a varied depth of field from shot to shot and this is in part what defines its most unique trait. Computer Chess features both tightly composed shots of heads bent over computer screens in a crowded room and long empty shots of a man dancing down a long hotel hallway. The camera itself is tethered to a recording box and then the film?s tech team was also simultaneously digitizing the image. This made the camera extremely bulky and immobile. Consequently, inside crowded rooms, the camera does not glide or dance with the actors like it does in modern films. The shots are often static and frames are often angled in such a way that it feels as if we don?t have unlimited access to these strange characters and their often obtuse arguments. The quality of the image could be called crude by comparison to today?s high resolution, high contrast, hypersensitive focus control cameras, but nevertheless, its unique vibe is both disorientating and transporting.

Bujalski?s film tells the story of a group of cutting edge computer geeks who gather in a Texas hotel for a computer chess tournament in the early 1980s. The team whose computer wins will face off in the final match for the ultimate man vs computer challenge, reminiscent of the actual Garry Kasparov chess challenges. There are an assortment of computer types with weird haircuts and unhip period clothes verbally sparring with each other about tech problems as well as larger esoteric questions regarding their own individual computers idiosyncrasies. Also in the hotel for the weekend is a marriage encounter couples therapy group who sit in a circle attempting to better understand their partners? and their own frustrations.

The couples? open eagerness to engage each other verbally about feelings is in stark contrast to the computer dweebs, who seem to each be stuck in some state of pre-adolescent, pre-verbal bubble. The contrast between these two groups is often mined for hilarious laughs, such as when one of the couples tries to seduce the youngest member of the computer tribe by getting him to ?open up? about his feelings and urges while rubbing his neck.

The dislocation caused by the physical aspects of the production, the weird haircuts, lingo, clothes and the black-and-white imagery transport you to a world that for sure existed but has never really been explored on the big screen with such texture. Unlike other films of this period, Computer Chess doesn?t attempt to evoke warm fuzzy nostalgic feelings of a bygone era; instead, it uses the dislocation generated by the video image to cause us to be hyper-aware of how different the world was in the past from how it is now. Bujalski depicts an innocent computer age when the excitement of technology was driven by a pure pursuit of exploration, rather than the pursuit of application value. At one point a programmer says the future of computers is in dating and we are reminded that there was a time when computer science had yet to be fully co-opted by the corporate consumer driven mentality that currently fuels the dreams of young tech geniuses.

The theme of Man versus Computer is in itself a quaint concept because it was driven by a now dated fear of technology. There were initially fears that computers could be used to create mass destruction or that man?s basic humanity would be somehow compromised by a HAL type computer logic. The film has a sad eve of destruction vibe to it; at times, it reminded me of another Texas indie film, Eagle Pennell?s Last Night At The Alamo, which was also about a group of people getting together for one last night before their world was changed (in this case, the closing of an old tavern). Likewise, Computer Chess depicts life on the cusp before the computers won. Today there are barely any skeptical voices who speak out against the evils of technology. Jaron Lanier?s book You Are Not A Gadget as well as J?rgen Habermas?s screeds against the internet are the lone articulations of this position. Computer Chess, though, is a comedy and it can be simply enjoyed as a nostalgic romp. But if you start to really explore your own insecurities about some of the conflicts that arise throughout the film?s weekend, you may be surprised how deep its tech themes really run. It?s an extremely entertaining low-tech cinematic breakdown of our modern high-tech world.

? Mike S. Ryan

Source: http://www.hammertonail.com/reviews/computer-chess-film-review/

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Sarah Palin and the End of an Era

The news that Sarah Palin will no longer be a paid contributor to Fox News puts an exclamation point on the end of an era, or at least a chapter, in U.S. political history. She could land somewhere else, and she still has her Facebook friends, but it?s hard to imagine she?ll find a more visible or influential platform than Fox.

The former Alaska governor and 2008 vice presidential nominee has been fading from the scene for some time, as she inadvertently highlighted when she complained on Facebook during the Republican convention in August that the network had canceled her scheduled interviews that night. Her brother, Chuck Heath Jr., told Alan Colmes last week on Fox Radio that his sister is ?kind of laying low right now,? though he wouldn?t or couldn?t say when asked why.

Once the face of an energetic and politically potent Tea Party movement, Palin is leaving Fox at a time when polls show the Tea Party at an all-time low in both membership and favorability. Her departure also coincides with calls by some leading Republicans for their party to stop saying things that erode the GOP brand and turn off voters in droves.

Louisiana Gov. Bobby Jindal said bluntly this week at a Republican National Committee meeting in Charlotte that the GOP needs to stop being ?the stupid party,? and former Mississippi Gov. Haley Barbour said he agreed. The two were talking in particular about losing Senate candidates Todd Akin of Missouri and Richard Mourdock of Indiana, both of whom made inflammatory (and in Akin?s case, flagrantly ignorant) comments about rape.

But Palin, with her flamboyant rhetoric, has stoked her own disproportionate share of controversies. This is the woman who, after all, coined the term ?death panels? to describe discussions between patients and physicians about end-of-life treatment (killing a bipartisan proposal for Medicare to reimburse doctors for having those talks); who complained of a ?blood libel? against her by ?journalists and pundits? after the Tucson shooting rampage that injured Gabrielle Giffords (the phrase historically relates to the charge that Jews murder children to use their blood in religious rituals); and who last fall accused Obama of ?shuck and jive? in his statements on the killings of U.S. diplomatic personnel in Benghazi (a racist term dating from slavery days).

Former secretary of state Colin Powell ripped Palin, though not by name, for the shucking-and-jiving remark. He said that and a characterization of Obama as "lazy" (by former New Hampshire governor John Sununu, also not cited by name) played into negative stereotypes of blacks and laid bare a ?dark vein of intolerance? within some parts of the GOP.

Palin defended herself by noting other political figures have used the phrase, including New York Gov. Andrew Cuomo and White House press secretary Jay Carney. That?s true, and it?s also true that outside of conservative media, Carney largely seems to have gotten a pass. But Cuomo was roundly criticized when he said it during the 2008 Democratic primary campaign (he was a Hillary Clinton supporter). In fact, during that bitter nomination contest, the media monitored every word from Clinton, her husband and her staff for evidence of racial politics. And we found a number of examples, some more valid than others.

The problem for Republicans is that Democrats nominated and elected a black president ? twice now ? while they are still trying to fight perceptions they are hostile to minorities and the policies they support. That makes comments like Palin?s particularly harmful.

The shuck-and-jive incident was one of many signs that Palin has not adapted to a changing political environment. Her Dec. 19 interview on On The Recordwith Greta Van Susteren, her final appearance on the network, was like a time warp back to 2008. She still makes up words (?electioning?). She still repeats sentences and phrases, padding her answers with filler. She still talks in vague generalities, leaving one to wonder how much she really knows. At a time when some conservatives reportedly have concluded it?s time to challenge liberalism rather than keep trying to stoke hostility toward Obama himself, she still attacks Obama in highly personal terms (?Mr. Nobel-Peace-Prize- winning president of ours?). Her diction is still, shall we say, unusual (?I believe that it?s many, many things that he would say and do being deceptive?).

Palin also still says weirdly inexplicable things.

When she first heard that Obama had been named Time magazine?s 2012 Person of the Year, she said her reaction was ?What the heck has he done really? What has he done except drive us over a fiscal cliff? ? Other than that, really, what has he done to unify and make our nation a more perfect union? For the life of me I don?t know, Greta.?

Obama of course has done a lot of things, some of them very polarizing. Palin had an opportunity to invoke Obamacare, gays in the military or any number of moves to back up her point about Obama dividing the nation and, in the view of many, making it less rather than more perfect. It was left to Van Susteren to add a little heft to the discussion, noting that Obama would deserve the designation if it had been awarded for winning a very difficult reelection campaign with a broad swath of demographic groups.

The strangest thing Palin said during that interview was her argument as to why Time?s recognition of Obama was irrelevant. Pointing to herself in seeming disbelief, she said that ?yours truly? had made the magazine?s list of the most influential people in the nation and world, and ?that ought to tell you something right there about the credence that we should give Time magazine and their list of people.? A bemused Van Susteren replied, ?All right. Well. That?s an interesting concept.?

Fox hired Palin three years ago ? at a reported $1 million a year ? because, Fox News Chairman Roger Ailes told The Associated Press, ?she was hot and got ratings.? While the terms of her departure are not public, it appears Fox came to the same conclusion as Palin about her diminishing role on the national and world stage.

Source: http://news.yahoo.com/sarah-palin-end-era-092711493--politics.html

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