Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/195784697?client_source=feed&format=rss
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Sunday, February 5, 2012
Back-to-back victories in hand, Romney looks ahead while Gingrich regroups (Star Tribune)
Saturday, February 4, 2012
Vet biotech aims at generic pet medicine market ? Health & Fitness ...
PORTLAND, Maine ? As Jean Hoffman?s cat, Dude, got older and more infirm, she began to see some of the failings of the veterinary medicine sector and opportunities to both help and build a business.
Hoffman had spent her career in the pharmaceuticals industry, both human and animal. As Dude aged and needed increasing vet medicines to stay healthy, Hoffman realized one big difference between veterinary pharmaceuticals and human: generic drugs were virtually nonexistent in the pet world.
In fact, Hoffman said, 94 percent of drugs for dogs and cats approved by the Food and Drug Administration have no equivalent generic version, while virtually every human drug for which the patent has expired has a generic.
?I saw a big need,? said Hoffman. ?I knew not everyone could afford to buy drugs costing $60 a month for their cat.?
Hoffman founded Putney Inc. in 2006 aimed at that market ? developing generic versions of companion animal drugs.
Hoffman?s business idea has gotten a strong vote of confidence from the investment world. Late last year, Putney received $21 million in third-round venture capital financing, following $12 million raised in two earlier rounds.
Putney added 10 employees last year and now has 22, with plans to hire another 10 this year. While she wouldn?t disclose exact numbers or specific areas of treatment, Hoffman said Putney has a pipeline of generic drugs currently under FDA review and expects ?multiple product approvals? within the next 24 months.
?That?s what will drive our future growth,? Hoffman said.
Hoffman said Putney is not looking for any future investment. With the approvals, she said, will come ?dramatic growth of revenues.?
According to an October 2011 report from market research firm Packaged Facts, the size of the U.S. pet medications market in 2011 was $6.68 billion, and is projected to reach $9.25 billion in 2015.
Putney has been working to identify the right generics to develop, said Hoffman, aiming at areas where there is a market need and where more pet owners may opt for treatment if there were a less-expensive alternative available.
Once the team identifies the drug to pursue, they next determine which human drug development organization has the right mix of formulation scientists and facilities to do the actual work.
Putney has opted to go with facilities that normally work on human drugs, Hoffman said, because those organizations will have kept up on the technology needed to meet ever-increasing FDA regulations, and are set up with high-quality plants that can quickly scale production when commercialization is needed.
Putney?s scientists manage external market development, product testing and the regulatory process. Essentially, they are outsourcing the production work to labs. The company also has licenses to sell two generics currently in the market, one for Ketamine, the other for Caprofen, both pain medications, and sells some FDA-approved human medicines that are used by veterinarians.
Broadly speaking, said Hoffman, drug areas of interest to Putney include anti-inflammatory drugs, pain relievers and parasiticides.
?If the owners can?t afford to put their pets on it, then we need to have a less expensive alternative ? it?s really that simple,? said Dr. Elizabeth Johnson, manager of product development.
Johnson is a vet who joined Putney in 2009, and runs the company?s studies that test its products alongside the brand-name drugs. She still works one day a week at a local vet clinic, and said she sees pet owners multiple times a day who can?t afford to pay for pet medications.
?If Putney can put out cost-effective FDA alternatives to these expensive medications, then everyone wins,? said Johnson. ?More pets get treated, the owners are happy, veterinarians are happy because they have clients leaving their offices without outrageous bills.?
Her colleague, Dr. Nancy Zimmerman, another vet and director of professional marketing, noted that the last recession hit vet clinics harder than they had been before. Clinics went bankrupt, doors were closed, and that hadn?t been seen in previous slowdowns, Zimmerman said.
Hoffman said in a down economy, pet owners make less vet visits. Animals can sicken and, when they finally get to the vet?s, are potentially in much worse shape than they would have been if they had visited earlier.
Putney has research showing that when vets can offer generic drugs, more owners bring their pets in more often, Hoffman said.
The venture capital infusion last year allowed Putney to bring on more employees and to start building its commercialization structure for when its drugs are approved. While many of the top experts Putney has hired have been from out of state, the company is looking to hire finance, customer service, inside sales and administrative positions from the Maine work force. That said, one of the top challenges Putney faces going forward is attracting the kind of top talent it needs to grow.
She noted, however, that one of the company?s top recent hires, TJ Dupree, the chief operating officer, came from another Maine vet biotech ? IDEXX Laboratories in Westbrook.
?There is a cluster growing up here around IDEXX,? Hoffman noted.
As COO, Dupree is first charged with developing that commercialization effort. There are challenges to that, he noted.
?We are a very small fish in a big pond full of sharks. There are a lot of branded pharma companies who we are challenging, and they are not interested in our success,? said Dupree. ?We have to recognize that while we have a fantastic message, getting that message to veterinarians and pet owners is ultimately work. We are going to have to do things differently ? leverage technology and social media in ways they have not.?
The pet generics market hasn?t been developed largely because it?s difficult to do so, said Hoffman, with high barriers to entry. But working with human drug companies has helped knock some of those barriers down, she said.
Dupree?s next challenge will be opening up global sales channels, and working Putney?s drugs through the regulatory processes in countries where ?pets are economically valued as well as emotionally valued,? he said.
?We see a great opportunity to build out ? not only to serve the U.S. market, but to take it globally,? said Hoffman, ?here from Maine.?
Source: http://bangordailynews.com/2012/02/03/business/vet-biotech-aims-at-generic-pet-medicine-market/
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Disadvantages and Advantages: Structured Settlements
February 3rd, 2012 by admin
Just like everything else in the world there are positive aspects and disadvantages of buying and selling structured settlements. Structured settlements are organized between two parties when the purchaser party is getting issues paying off their debts to the borrowers or creditors.
These settlements improve ensure timely payments from the client?s end and make certain the money they save for their debits is focused for that specific purpose.
There is yet another direction or way in which structured settlements are applied. This is for you own good. For example a minor person who has suffered an injury and has to undergo a long term medical process can buy a structured settlement and make timely deposits to it.
Depending on what the terms of the agreement are he or she will be paid specific amounts of money in specific time intervals which will improve them save up and have money especially for their treatment.
In this case these folks will not need to be concerned about over spending or not being able to save enough. These structured settlements are especially effective for retirement times.
People can start depositing specific amounts of money when these folks are in the early to mid forties and by the time they hit their sixties they will not need to work anymore. It will permit them to lead a peaceful and work free life. Their stress levels will vastly lessen and it will be really good. Even for folks who are ambitious and feel they may possibly call for a lump sum amount of capital for their future plans can start saving up with structured plans.
These are all the sugar coated amazing facts of structured settlements; however like every little thing else there are a few negatives. These are not demeaning to anyone by any means; however are things that need to be considered in order for individuals to be cautious with their money and get the greatest out of their settlement.
One of the setbacks of a structured settlement is that it limits your overall amount of expenditure. This is not your daily grocery expenditure, rather money you would shell out on buying things like a new home or perhaps a new car. You will be restricted to do this because of your overdue debt.
In addition to that it can become quite difficult for you to be capable to buy anything against you outstanding settlement and debts particularly if you call for a bank loan. No bank will even look at offering you a loan with bad debt lying around the corner and a settlement for you to resolve. This is just a settlement you may have against a debtor, what is structured settlement.
If you are investing money for you future, it can be yet another predicament. about structured settlements?This is simply because you will not be able to withdraw the money once you deposit it simply because it goes into a secure account. You will only receive once it is time for your installment. Also, due to the fact you are expected to pay money in this case to save up you will not be capable to shell out it elsewhere, about structured settlements.
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Source: http://www.gapagos.com/finance/disadvantages-and-advantages-structured-settlements/
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Friday, February 3, 2012
Altlanta ga International airport Fancy car Services in Hire at ...
Atlanta?s one of many popular luxurious limos about rental service provider be it on corporate and business as well as leisure degree are usually Atl Auto Fancy car Solutions, who are growing prematurely throughout the world.
Be this a marriage or one impressive situations someone who comes out of the Limo appears diverse within the crowd and everyone would like always be that different Limousine Service. Altlanta ga Automobile Limo Companies would be the company of Limousine leases in Altlanta ga. Whether you?re at virtually any degree ? corporate or even amusement they?re recognized with regard to Limousine providers throughout Altlanta ga. Their own and high report solutions make them not the same as others. Not really throughout Altlanta ga merely but all over the world The atlanta area Car chauffeur driven car companies makes available skilled drivers using a high quality transport services. That is the reason it can be rapidly expanding around the world. It warranties quick and quality services each time.
Mainly Limousine rental fees Atl Vehicle provide/use these types of types:
Chrysler 3 hundred Stretch
Lincoln Stretch out (into two colors- monochrome)
Frd Expedition
H2 Hummer Stretch
15 Traveling Van
28 Travellers Limousine Coach
36 People Chauffeur driven car Coach
You have got different great possibilities from where you are able to select in line with the dependence on your occasion. Below you?ve got the facility regarding reserving online that is quite simple and simply in Three moments your reserving will be done. You can publication online everywhere you look across the nation for which you must join a merchant account together. Having an accounts it is possible to get each and every specifics in connection with your trip, an individual quickly may have a seem onto the prices according to the area. They?re available about each event, each day for 24 hours. Having an accounts using them it is simple to take a glance on to your present in addition to earlier costs statements. In your pay a visit to as well as trip to diverse unfamiliar location, you can also get aid from Altlanta ga Vehicle Chauffeur driven car Companies. They will manual with regards to something more important like college accommodation, Rental car, meal reservation, contributing to the airfare position (on the internet). They will offer door to door companies. That they promise to the 100% on time arrival in any other case free journey is given since compensation to each buyers.
You ?ve got a variety of fantastic possibilities from which you can select in line with the requirement of your occasion. The following you?ve gotten the facility regarding reserving online which is a breeze and within Three or more moments the booking could be carried out. You can publication on the web everywhere across the nation that you should subscribe to a free account with these. With the accounts it is possible to possess every details in connection with your vacation, anyone immediately could have a appear to the prices according to the metropolis. They are wide open in each occasion, every single day every day and night. With the account together you can actually take a glance on to your current and also past expenses assertions. Within your check out or even a vacation in various not known location, you may even consider aid from Altlanta ga Automobile Chauffeur driven car Providers. These people information about something more important such as hotel room, Car hire, meal booking, leading to your own airline flight status (on the internet). They even provide door-to-door solutions. That they ensure for your 100% promptly appearance normally totally free trip is given because compensation to each and every clients.
Atlanta?s one of many popular luxurious limos about rental service provider be it on corporate and business as well as leisure degree are usually Atl Auto Fancy car Solutions, who are growing prematurely throughout the world.
Be this a marriage or one impressive situations someone who comes out of the Limo appears diverse within the crowd and everyone would like always be that different. Altlanta ga Automobile Limo Companies would be the company of Limousine leases in Altlanta ga. Whether you?re at virtually any degree ? corporate or even amusement they?re recognized with regard to Limousine providers throughout Altlanta ga Limo Services. Their own and high report solutions make them not the same as others. Not really throughout Altlanta ga merely but all over the world The atlanta area Car chauffeur driven car companies makes available skilled drivers using a high quality transport services. That is the reason it can be rapidly expanding around the world. It warranties quick and quality services each time.
Mainly Limousine rental fees Atl Vehicle provide/use these types of types:
Chrysler 3 hundred Stretch
Lincoln Stretch out (into two colors- monochrome)
Frd Expedition
H2 Hummer Stretch
15 Traveling Van
28 Travellers Limousine Coach
36 People Chauffeur driven car Coach
You have got different great possibilities from where you are able to select in line with the dependence on your occasion. Below you?ve got the facility regarding reserving online that is quite simple and simply in Three moments your reserving will be done. You can publication online everywhere you look across the nation for which you must join a merchant account together. Having an accounts it is possible to get each and every specifics in connection with your trip, an individual quickly may have a seem onto the prices according to the area. They?re available about each event, each day for 24 hours. Having an accounts using them it is simple to take a glance on to your present in addition to earlier costs statements. In your pay a visit to as well as trip to diverse unfamiliar location, you can also get aid from Altlanta ga Vehicle Chauffeur driven car Companies. They will manual with regards to something more important like college accommodation, Rental car, meal reservation, contributing to the airfare position (on the internet). They will offer door to door companies. That they promise to the 100% on time arrival in any other case free journey is given since compensation to each buyers.
You ?ve got a variety of fantastic possibilities from which you can select in line with the requirement of your occasion. The following you?ve gotten the facility regarding reserving online which is a breeze and within Three or more moments the booking could be carried out. You can publication on the web everywhere across the nation that you should subscribe to a free account with these. With the accounts it is possible to possess every details in connection with your vacation, anyone immediately could have a appear to the prices according to the metropolis. They are wide open in each occasion, every single day every day and night. With the account together you can actually take a glance on to your current and also past expenses assertions. Within your check out or even a vacation in various not known location, you may even consider aid from Altlanta ga Automobile Chauffeur driven car Providers. These people information about something more important such as hotel room, Car hire, meal booking, leading to your own airline flight status (on the internet). They even provide door-to-door solutions. That they ensure for your 100% promptly appearance normally totally free trip is given because compensation to each and every clients.
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Source: http://burgessboy.com/?p=4115
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Exploring Immediate Products Of Fireplaces and Woodstoves
Home improvements are important to add value to your house. Not only that, they are necessary in keeping your home in tip-top shape. There are many things that you can do to enhance your living space, and some projects are more complex than others. Read this article for some suggestions.
Woodstove Points
Instead of installing electricity based heating system in your home, consider going with a large wood stove. With the proper woodstove pipe and the right size, a wood burning stove is more cost effective and heats better. If the electricity ever goes out, you are still able to keep warm in the winter.
To prevent animals like birds or squirrels from nesting in your chimney, install a chimney cap. These devices feature mesh sides that allow smoke to escape, but the solid top prevents animals from entering your chimney to build nests, which can ignite and cause a chimney fire when you use woodstove insert.
Have your chimney cleaned and inspected prior to using your woodstove each year. The inspector can look for creosote build-up, cracks in the lining, nests from animals or other problems that could spell disaster. A chimney sweep will use long brushes to thoroughly clean your chimney and remove debris that could catch on fire.
More Woodstove Conclusions
If you are considering installing a woodstove for heating your home, understand that this is a much better route than adding a conventional fireplace. Apart from aesthetic reasons, this type of system is also quite efficient because most of the heat ends up in your home instead of going through the chimney as it does with an open fireplace. In addition to this, the fireplace requires plenty of fresh air, which will be provided from within your house, essentially eating up much of the oxygen inside your home, whereas modern wood burning stoves are air-tight and require very little air from your living space.
To create a modern focal point in your living room or study, consider installing a new stone, brick, or wood mantel for the area above your fireplace. If your fireplace already has a mantel, you can have it sanded and refinished to change its look. You could also update it by staining the brick or concrete with a rich color.
Final Woodstove Decisions
If you are doing work near a kitchen, fireplace, or gas appliance, make sure you know where the gas shutoff for your home is located. If there were to be an accident, and gas started leaking into your home, the smallest spark could set it off. If you know in advance where the shutoff is, you can respond faster to the issue before it becomes an emergency.
When you are improving your house, remember to keep things in perspective. Ask yourself why you want to make a specific improvement, and think about how the project that you want to tackle will improve your quality of life. Home improvement requires commitment, and you want to be sure that you are investing your time and money into something worthwhile.
Source: http://bestofphoenix2009.com/exploring-immediate-products-of-fireplaces-and-woodstoves
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Thursday, February 2, 2012
LG's triple SIM A290: the phone every Russian Casanova needs
Dual-SIM phones are perfect for when the carriers are desperate for your business, keeping your work life separate, or to mask your philandering -- but what if two isn't enough? LG (stands for Lucky Goldstar, now you know) is producing a phone with a third SIM slot, only one less than the ridiculously equipped OTECH F1. The A290 candy-bar throwback sports a 176 x 220, 2.2-inch display, 1.3 megapixel camera, LED flashlight and a 1500 mAh battery. Russians (for it's exclusive to the nation) looking to swell their SIM collection can do so from next month at the cost of €75 ($100).
LG's triple SIM A290: the phone every Russian Casanova needs originally appeared on Engadget on Tue, 31 Jan 2012 18:07:00 EDT. Please see our terms for use of feeds.
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