Internet Marketing Agency Ajax Union Introduces New PPC Feeder ...

Ajax Union, a boutique online marketing firm, is spotlighting new plans available for its PPC campaign management service.

New York, NY (PRWEB) February 03, 2013

Boutique internet marketing agency Ajax Union, available online at http://www.AjaxUnion.com, is now featuring updated Pay-Per-Click, or PPC, advertising and management plans to new and ongoing clients. The company?s PPC feeder program is a comprehensive pay-per-click management service, covering every aspect of a successful campaign. Pay-per-click advertising places businesses in the sponsored results of search engine results, allowing clients who are still building optimized websites and profiles to claim space on the critical first page of Google and other leading search engines.

Staffed by a team of Google AdWords certified professionals, the online marketing firm offers its PPC management plans in three separate levels, allowing small businesses to choose how much they wish to invest in paid search advertising. The PPC Saver Plan, starting at just $500 provides an initial starting point for an investment in pay-per-click ads, allowing customers a monthly ad spend of up to $1,500. The PPC Basic and PPC Pro Plans offer expanded options for creating and customizing advertising plans, priced, respectively, at $750 and $1,500 per month.

?Pay-per-click advertising is a great solution for new businesses, or those focusing on especially competitive keywords. With professional and proven PPC marketing strategies, a new company?s ads can appear as frequently and prominently as those run by its competitors. Our experts assist clients with every step of the process, from creating stellar advertising copy to providing detailed reports and carefully monitoring each campaign in progress. The PPC plans allow every business to make the most of an online advertising budget and achieve more clicks, impressions, and conversions,? said Google AdWords specialist and Agency Manager David Gscheidle.

PPC plans are just one of Ajax Union?s many small business Internet marketing services. In addition to paid search advertising, the company offers search engine optimization programs to help clients improve website rankings in organic search results. Email marketing, video promotions, and press release distribution are all services available on a month-to-month basis from the Brooklyn, NY-based agency. In addition, the company offers its clients a number of helpful online applications, such as the keyword analysis tool RankZen. Ajax Union operates with complete transparency and consults its customers on each decision, soliciting and applying client feedback while managing plans.

To learn more about PPC campaign management plans and the array of other available services, visit the SEO company online or call 1-800-594-0444. The company can also be found on Facebook and Twitter.

For the original version on PRWeb visit: http://www.prweb.com/releases/prwebajax-union/seo-company-ppc-feeder/prweb10389445.htm

Source: http://pressreleases.bloginteract.com/2013/02/internet-marketing-agency-ajax-union-introduces-new-ppc-feeder-plans-to-offer-companies-affordable-professional-pay-per-click-ad-management/

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Gene therapy: Editing out genetic damage

Jan. 31, 2013 ? New design guidelines from researchers in Singapore simplify the development of targeted therapies for muscular dystrophy and other diseases.

The dystrophin protein offers critical support to muscle fibers. Mutations affecting dystrophin's expression cause the muscle-wasting disease muscular dystrophy. In Duchenne muscular dystrophy (DMD), these mutations take the form of small sequence changes that make much of the dystrophin gene (DMD) untranslatable, yielding nonfunctional protein or no protein at all.

Therapies based on a strategy known as 'exon skipping' could undo the damage from these mutations. Development of such treatments is set to accelerate, thanks to research by a team led by Keng Boon Wee of the A*STAR Institute of High Performance Computing and Zacharias Pramono of the National Skin Centre in Singapore.

Proteins are translated from messenger RNA transcripts of genes; however, only certain RNA regions -- known as exons -- actually encode protein, and these are enzymatically spliced together prior to translation. Several clinical studies have demonstrated that small 'antisense oligonucleotide' (AON) molecules that bind mutated DMD exons can induce elimination of those defective exons during splicing, yielding shorter but largely functional versions of dystrophin. "We are cautiously optimistic that AON-induced exon skipping could be the first effective therapy for DMD patients," says Wee.

Unfortunately, DMD arises from many different mutations, and targeted AON design remains a time-consuming, trial-and-error process. To address this challenge, Wee and Pramono sought to define the characteristics of AONs that efficiently promote exon-skipping. They used computational analysis to zoom in on exonic sequences that coordinate splicing. They also identified regions of suitable length within dystrophin RNA transcripts that span these sequences and would be accessible to AONs in living cells.

The researchers thus derived a set of guidelines enabling them to effectively design AONs that targeted nine different exons affected in DMD patients. For each exon, at least one AON proved capable of boosting dystrophin expression to clinically relevant thresholds in cultured muscle cells (see image). "Our proposed set of factors resulted in a reasonable success rate of designing efficient AONs -- 61% versus 38% using semi-empirical methods," says Wee. Clinical studies have already demonstrated the promise of efficient exon skipping in treating DMD patients.

Wee notes that other diseases arising from abnormal RNA processing could also benefit from this approach. However, his team is also exploring this method as a general strategy to abort production of disease-causing proteins in cancer and other conditions. "In contrast to small-molecule inhibitor drugs that can target only about 10% of the human genome, this approach could downregulate most human genes," Wee says.

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Story Source:

The above story is reprinted from materials provided by The Agency for Science, Technology and Research (A*STAR).

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Pramono, Z. A. D., Wee, K. B., Wang, J. L., Chen, Y. J., Xiong, Q. B. et al. A prospective study in the rational design of efficient antisense oligonucleotides for exon skipping in the DMD gene. Human Gene Therapy, 2012 DOI: 10.1089/hum.2011.205

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/p2_gTFzETgw/130203145430.htm

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Montana man made up sob story that got him pizza

HELENA, Mont. (AP) ? A Montana man whose tearful reluctance to rob a pizza restaurant earned him free food apparently made up the sob story that gained him the clerk's sympathy.

David Randall Lacey, 35, entered a Papa John's pizza restaurant on Jan. 22 with a bandanna over his face and gave the clerk a note demanding money, Helena police said. He broke down crying and told the clerk he needed the money to support his wife and children, who were hungry. The clerk made him a large pepperoni pizza and some chicken wings as he waited, and the man left.

The Independent Record reports (http://bit.ly/14vlTZr) an investigation found Lacey has no children in Helena and changed his story when he saw how little money was in the cash register ? just $24.56, according to a police report.

Police received a tip that Lacey acknowledged his role in the incident and a clerk picked him out of a lineup. He was arrested Thursday on suspicion of felony robbery. He remained jailed Friday with bail set at $25,000.

Lacey told police he needed the money to buy food, court records said.

___

Information from: Independent Record, http://www.helenair.com

Source: http://hosted2.ap.org/APDEFAULT/aa9398e6757a46fa93ed5dea7bd3729e/Article_2013-02-01-Reluctant%20Thief/id-045e7c2597be420f99dd146c0666b234

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Sylvester Stallone Supports Gun Control: 'Bullet To The Head' Star Doesn't See Value In Assault Weapons

BEVERLY HILLS, Calif. ? Sylvester Stallone says that despite his "Rambo" image and new shoot-em-up film "Bullet to the Head," he's in favor of new national gun control legislation.

Stallone supported the 1994 "Brady bill" that included a now-expired ban on assault weapons, and hopes that ban can be reinstated.

"I know people get (upset) and go, `They're going to take away the assault weapon.' Who ... needs an assault weapon? Like really, unless you're carrying out an assault. ... You can't hunt with it. ... Who's going to attack your house, a (expletive) army?"

The 66-year-old actor, writer and director said he also hopes for an additional focus on mental health to prevent future mass shootings.

"It's unbelievably horrible, what's happened. I think the biggest problem, seriously, is not so much guns. It's that every one of these people that have done these things in the past 30 years are friggin' crazy. Really crazy! And that's where we've dropped the ball: mental health," he said. "That to me is our biggest problem in the future, is insanity coupled with isolation."

Stallone is now in production on his next project, pairing up with the former "Raging Bull" Robert De Niro for "Grudge Match," about two aging boxers.

"People think it's going to be some geezer brawl. Really? OK, they're in for a surprise. I'm telling you. I've been working on the fight, the choreography. He's taking it deadly serious. Because no one wants to be shown up," Stallone said of De Niro. "It's going to be like a `Rocky' fight. This will be `Rocky 7,' with me fighting ? with Rocky fighting the `Raging Bull.'"

___

Follow AP Entertainment Writer Ryan Pearson: http://twitter.com/ryanwrd

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Source: http://www.huffingtonpost.com/2013/02/01/sylvester-stallone-gun-control_n_2602644.html

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Study Says Romance Can Last In Long-Term Relationships | World ...

This guest article from YourTango was written by Teresa Maples.

Have you settled for companionship in your would-be romantic relationship? Companionship is when you exist in the same home but spend very little time together, and neither of you is particularly satisfied.

Take the stereotypical man-watching-football-while-his-wife-cleans-the-house scenario. She resents that he gets to relax while she slaves to keep the home clean. She complains about him watching football and not helping around the house. He becomes angry and they either argue or physically go to separate rooms to get away from each other. Does this sound familiar?

The good news is that romance doesn?t have to die in your long-term relationship. Find out how below.

As a licensed mental health counselor, I?ve heard countless renditions of the scenario above, where wives and husbands are convinced that companionship?is as good as it gets for married life. Out of desperation, they ask me for help, and here?s what I say.

Research shows that long-term couples who strive for ?love with all the trimmings? enjoy more satisfying relationships. It all starts with this first question: Do you want to be more satisfied in your long-term relationship? If your answer is ?no, ?then stop right here and do not read another word. Keep reading if you would like a more satisfying relationship; it takes awareness and intention to make it happen.

Here are three ways you can foster sparks in your long-term relationship:

1. Ask directly for your needs to be met.

Your partner cannot read your mind. Become aware of your emotional and behavioral patterns in the relationship. Those who pursue often have a fear of abandonment; those who avoid often have a fear of being consumed by another person. Those two types often hook up in relationships.

The pursuer?s greatest need is to feel emotionally connected with his/her partner. The avoider?s greatest need is to stay away from emotional connection. These are opposing needs.

Each person needs to address his/her own fears in the relationship. The pursuer needs to find a way to cope with his/her fear of abandonment and make emotional space for the avoider to take action. The avoider needs to face his/her fear of being overwhelmed emotionally and bridge the emotional gap between him/her and the pursuer. Finding a healthy balance is attainable.

2. Be respectful of yourself and your partner at all times.?

Take a time out if you feel angry or resentful. Journal about your resentments and try to find a solution before talking to your partner. Learn to articulate your feelings in a non-threatening way. Be ready for your partner to say your solution doesn?t work. Ask for his/her solution; he/she might have a great idea. Be a safe person for your partner. Your partner can be your best ally and friend.

3. Choose to bring novelty to your relationship.?

Bring home flowers, take each other on a date, go on an adventure together, spend time doing a project together, ski, hike, bike, craft, take photos of birds ? you get the idea.

It is vitally important to remember your goal of being satisfied in your relationship. Helping your partner feel emotionally safe with you is the key to your satisfaction in a long-term relationship. Bringing novelty will spark the flames of romance only if you both feel emotionally safe and connected.

If you would like more information to make your Couple-ship Thrive please sign up for my newsletter. You may also connect with me on my website Teresa Maples LMHC, CSAT and on Twitter.

?

More relationship advice from YourTango:

?

Senior couple photo available from Shutterstock

Contributed by YourTango.com, an online magazine dedicated to love, life and relationships. From dating to marriage, parenting to empty-nest, relationship challenges to relationship success, YourTango is at the center of the conversations that are closest to our over 3 million readers' hearts. With daily contributions from our Experts, we have a little something for everyone looking to create healthier lives. We're excited to offer our contributions to the PsychCentral community, and invite you to visit us on YourTango.com.

Like this author?
Catch up on other posts by YourTango Experts (or subscribe to their feed).

????Last reviewed: By John M. Grohol, Psy.D. on 2 Feb 2013
????Published on PsychCentral.com. All rights reserved.

APA Reference
Experts, Y. (2013). Does Romance Have to Die in Your Long-Term Relationship?. Psych Central. Retrieved on February 3, 2013, from http://psychcentral.com/blog/archives/2013/02/02/does-romance-have-to-die-in-your-long-term-relationship/

?

Source: http://psychcentral.com/blog/archives/2013/02/02/does-romance-have-to-die-in-your-long-term-relationship/

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Magnetic Transistor Could Cut Power Consumption and Make Chips Reprogrammable

one that requires voltage to keep it on, one that requires voltage to keep it off (P channel vs N channel FET's), ones that require current levels to keep it on and off (npn and pnp BJT's)

so to say

"First, keeping the voltage on requires power"

is a broad statement, yea something that uses power requires power

Then

"Second, transistors must be hard-wired into the chips and can't be reconfigured"

well yea, but we have long established configurations of transistors that can be reconfigured to suit needs, its calle

Source: http://rss.slashdot.org/~r/Slashdot/slashdotScience/~3/6w9E7uTwzUU/story01.htm

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San Francisco 49ers' Road To Super Bowl XLVII

Jim Harbaugh's decision to switch quarterbacks during the San Francisco 49ers' season made all the difference to the two players involved, but you'd hardly tell that such a monumental shift occurred merely by looking at the team's win-loss record.

With Alex Smith under center, the 49ers opened up with a 6-2 record. In their first game back from a Week 9 bye, Smith suffered a concussion against the Rams and second-year, second-stringer Colin Kaepernick took over. That game resulted in a rare tie but San Francisco soon got back to its winning ways. Following two straight Kaepernick-powered wins, Harbaugh chose to go with the "hot hand" even though Smith was available. A week later, coming off a loss to the Rams, Harbaugh decided to stick with Kaepernick and never looked back.

The result? Kaepernick went 5-2 as the starting quarterback to finish the regular season, then delivered two stunning performances in the playoffs leading the 49ers to Super Bowl XLVII.

Before Super Bowl XLVII kicks off, take a look back the 49ers' road to New Orleans:

• Week 1 vs. Green Bay Packers

  <a href="http://www.huffingtonpost.com/2012/09/09/49ers-packers-30-22-san-francisco-defense-rodgers_n_1869316.html">49ers won 30 - 22.</a>

• Week 2 vs. Detroit Lions

  <a href="http://www.huffingtonpost.com/2012/09/16/49ers-lead-lions-179-afte_n_1889048.htmlmQ">49ers won 27 - 19.</a>

• Week 3 vs. Minnesota Vikings

  <a href="http://www.huffingtonpost.com/2012/09/23/vikings-stun-49ers-24-13-christian-ponder_n_1907917.html">49ers lost 24 - 13.</a>

• Week 4 vs. New York Jets

  <a href="http://www.huffingtonpost.com/2012/09/30/san-francisco-49ers-ny-jets-colin-kaepernick_n_1927264.html">49ers won 34 - 0.</a>

• Week 5 vs. Buffalo Bills

  <a href="http://www.huffingtonpost.com/2012/10/07/san-francisco-49ers-buffalo-bills-alex-smith_n_1946978.html">49ers won 45 - 3.</a>

• Week 6 vs. New York Giants

  <a href="http://www.huffingtonpost.com/2012/10/14/giants-49ers-26-3-alex-smith-interceptions-eli_n_1965652.html">49ers lost 26 - 3.</a>

• Week 7 vs. Seattle Seahawks

  <a href="http://www.huffingtonpost.com/2012/10/18/49ers-seahawks-13-6-frank-gore-san-francisco_n_1983854.html">49ers won 13 - 6.</a>

• Week 8 vs. Arizona Cardinals

  <a href="http://www.huffingtonpost.com/2012/10/29/san-francisco-49ers-cardinals-alex-smith-randy-moss_n_2042475.html">49ers won 24 - 3.</a>

• Week 10 vs. St. Louis Rams

  <a href="http://www.huffingtonpost.com/2012/11/11/rams-49ers-tie-nfl-overtime-greg-zuerlein_n_2115163.html">49ers tied 24 - 24.</a>

• Week 11 vs. Chicago Bears

  <a href="http://www.huffingtonpost.com/2012/11/19/san-francisco-49ers-kaepernick-bears_n_2162506.html">49ers won 32 - 7.</a>

• Week 12 vs. New Orleans Saints

  <a href="http://www.huffingtonpost.com/2012/11/25/49ers-beat-saints-31-21-kaepernick-defense_n_2189392.html">49ers won 31 - 21.</a>

• Week 13 vs. St. Louis Rams

  <a href="http://www.huffingtonpost.com/2012/12/02/rams-49ers-16-13-overtime-greg-zuerlein_n_2228687.html">49ers lost 16 - 13.</a>

• Week 14 vs. Miami Dolphins

  <a href="http://www.huffingtonpost.com/2012/12/09/49ers-dolphins-27-13--colin-kaepernick-gore_n_2268680.html">49ers won 27 - 13.</a>

• Week 15 vs. New England Patriots

  <a href="http://www.huffingtonpost.com/2012/12/17/49ers-patriots-kaepernick-crabtree_n_2313438.html">49ers won 41 - 34.</a>

• Week 16 vs. Seattle Seahawks

  <a href="http://www.huffingtonpost.com/2012/12/23/seahawks-49ers-russell-wilson-playoffs_n_2357431.html">49ers lost 42 - 13.</a>

• Week 17 vs. Arizona Cardinals

  <a href="http://www.huffingtonpost.com/2012/12/30/49ers-nfc-west-title-cardinals_n_2386333.html">49ers won 27 - 13.</a>

• Divisional Playoffs vs. Green Bay Packers

  <a href="http://www.huffingtonpost.com/2013/01/12/49ers-packers-colin-kaepernick-playoffs_n_2465387.html">49ers won 45 - 31.</a>

• NFC Championship vs. Atlanta Falcons

  <a href="http://www.huffingtonpost.com/2013/01/20/49ers-super-bowl-falcons-nfc-title_n_2517219.html">49ers won 28 - 24.</a>

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Source: http://www.huffingtonpost.com/2013/02/02/san-francisco-49ers-road-super-bowl-xlvii_n_2602185.html

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